| Name | FENCHLORPHOS |
| Synonyms | RONNEL ETROLENE DOW ET-14 KORLAN(R) NANKOR(R) RONNEL(R) FENCHLORPHOS O,O-DIMETHYL O-(2,4,5-TRICHLOROPHENYL) PHOSPHOROTHIATE |
| CAS | 299-84-3 |
| EINECS | 206-082-6 |
| Molecular Formula | C8H8Cl3O3PS |
| Molar Mass | 321.55 |
| Density | 1.485 g/cm3 (25 ºC) |
| Melting Point | 41.0℃ |
| Boling Point | 97℃ |
| Flash Point | -18 °C |
| Water Solubility | 40mg/L(room temperature) |
| Vapor Presure | 5.29 at 20 °C, 18.6 at 30 °C (Freed et al., 1977) |
| Appearance | Morphological solid color, white to light brown, waxy solid |
| Storage Condition | APPROX 4°C |
| Refractive Index | 1.5585 (589.3 nm 20℃ |
| Physical and Chemical Properties | Chemical properties white crystalline powder. Melting point 40-42 ℃, boiling point 152-154 ℃,97 ℃(1.33 × 10-3kPa), relative density 1.4575(50/4 ℃), refractive index 1.5530(50 ℃). The vapor pressure at 25 ℃ is 1.1 × 10-4kPa. Easily soluble in acetone, carbon tetrachloride, ether, chloroform, etc., hardly soluble in water. It is stable in neutral and acidic media, but it is easy to hydrolyze and lose insecticidal activity in alkaline media. |
| Use | The sulfur of the skin fly has a good insecticidal effect on a variety of pests, and has the effect of inhalation and fumigation in animals. In general, it is mainly used in the insect repellent. Due to the high vapor pressure, this product is effective against health pests, such as houseflies, and can be stored in an open container for 12-16 weeks. At the same time because of low toxicity, can be used in food processing plants to kill flies, in addition, the use of this product fumigation can effectively control food pests. For agricultural pests such as wheat straw flies, the control effect is similar to that of trichlorfon, and the control of diamondback moth can reach 94.5%. |
| Risk Codes | R21/22 - Harmful in contact with skin and if swallowed. R50/53 - Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. R67 - Vapors may cause drowsiness and dizziness R65 - Harmful: May cause lung damage if swallowed R38 - Irritating to the skin R11 - Highly Flammable |
| Safety Description | S25 - Avoid contact with eyes. S36/37 - Wear suitable protective clothing and gloves. S60 - This material and its container must be disposed of as hazardous waste. S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. S62 - If swallowed, do not induce vomitting; seek medical advice immediately and show this container or label. |
| UN IDs | UN 1145 3/PG 2 |
| WGK Germany | 3 |
| RTECS | TG0525000 |
| HS Code | 29201900 |
| Toxicity | LD50 in male, female rats (mg/kg): 1250, 2630 orally (Gaines) |
| Raw Materials | 2,4,5-Trichlorophenol o-(2,4,5-trichlorophenyl) phosphorodichloridothioate Parathion-methyl DICAPTHON Dimethyl chlorothiophosphate Fenitrothion |
| Downstream Products | FENCHLORPHOS-OXON |
biological activity
Fenchlorphos is an organophosphate insecticide. Fenchlorphos is an inhibitor of acetylcholinesterase (AChE). Fenchlorphos can cause mitochondrial dysfunction.
production method
It is obtained by the condensation of 2,4, 5-trichlorophenol and O,O-dimethyl thiophosphoryl chloride. Add 2,4, 5-trichlorophenol and 25% sodium hydroxide into the reaction pot, stir, heat to 50-60 ℃, and dissolve them all. Cold to 45 ℃, drop O,O,-dimethyl thiophosphoryl chloride, after dropping at 45 ℃ stirring for 10min. Heat up to 65 ℃ for 20min. Cold to 40 ℃, add 10% sodium hydroxide solution. Continue to cool, precipitate thion and phosphorus crystals of skin flies, and filter at 13.5-14.5 ℃. Wash with water, 0.75% (volume) hydrochloric acid solution and water in turn to obtain crude products. Recrystallization with ethanol to obtain a white finished product with a yield of about 95%.
category
Pesticides
toxicity classification
Poisoning
acute toxicity
oral-rat LD50: 625 mg/kg; oral-mouse LD50: 2000 mg/kg
flammability hazard characteristics
Fire site is heated to decompose toxic phosphorus oxide, sulfur oxide, chloride gas
storage and transportation features
The warehouse is ventilated and dry at low temperature; stored and transported separately from food raw materials
fire extinguishing agent
Sand, dry powder, foam
occupational standards
TWA 10 mg/m3
| toxic substance data | 299-84-3(Hazardous Substances Data) |
| immediate threat to life and health concentration | 300 mg/m3 |
| solubility | Soluble in acetone, carbon tetrachloride, ether, kerosene, methylene chloride, and toluene (Windholz et al., 1983) |
| Merck | 13,8337 |
| BRN | 1885571 |
| Henry's Law Constant | 8.46 at 25°C (approximate - calculated from water solubility and vapor pressure) |
| exposure limit | NIOSH REL: TWA 10 mg/m3, IDLH 300 mg/m3; OSHA PEL: TWA 15 mg/m3; ACGIH TLV: TWA 10 mg/m3. |
| EPA chemical information | Ronnel (299-84-3) |